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Stopping treatment abruptly or without a tapering and maintenance strategy can lead to weight regain

The glucose lowering effects of tirzepatide exceed those of most other GLP-1 agonists due to the additional GIP receptor activation

Depression was the most commonly reported event, with 187 cases accounting for 50.3% of psychiatric reports

During this phase, people usually stay on each dose for about four weeks before increasing it

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Interestingly, in chronic hyperglycemia, IR, T2D, and obesity, the GIP signaling is impaired and not able to inhibit appetite and metabolic derangements (Bergmann et al