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Front Endocrinol 8:6 Christensen M, Knop FK, Vilsbll T, Holst JJ (2011) Lixisenatide for type 2 diabetes mellitus

Lane 2 is biomimetic GLP-1 supplements (eg: yeast-delivered peptides)
Molecular-level observations also add to the evidence that GLP-1 is active in the brain

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Studies with a mean age of less than 65 were excluded

Comparing Common and Rare Side Effects When evaluating leg pain, it helps to see where it fits within the broader landscape of semaglutide side effects