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Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis

The primary endpoint was all-cause mortality at one year

Still, with the recent introduction of oral semaglutide (Rybelsus), accessibility has improved

Future studies should assess whether the metabolic reprogramming induced by GLP-1RAs exhibits dose-dependent characteristics and employ bibliometric approaches to investigate the temporal patterns of these metabolic changes

Oral weight loss medications are also preferred by people with a needle phobia or who dont feel confident self-administering an injection

M., Bgevig, S., Riis, T., Andersson, N