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Average weight loss ranges from 1015% of body weight over 12 weeks with consistent semaglutide use, though individual timelines vary widely based on starting weight, genetics, and adherence

It is a complex, chronic disease influenced by biology, environment, stress, trauma, and access to care

A person with a BMI of 28 and a history of gestational diabetes may benefit from one of these medications to lose weight while concomitantly mastering lifestyle behaviors, and then transition off the weight management medications to lifestyle alone, says Linda Gigliotti, MS, RDN, CDCES, CSOWM, an obesity and weight management specialist based in Irvine, California

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GLP-1 is a peptide hormone consisting of 30 amino acids derived from glucagonogen, which is processed by the differentiation of the glucagonogen gene expressed by intestinal epithelial endocrine L-cells, and has two biologically active forms, GLP-1 (736 amide) and GLP-1 (7-37), and the intestine is the major source of GLP-1 in plasma (Mller et al., 2019

Medication may not be appropriate for everyone