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1.It stimulates insulin secretion from pancreatic -cells

Rang and Dale's Pharmacology (8th ed.)

By coupling GLP1-R agonist and GIP agonist together (seen in Tirzepatide), reduced reward-seeking behavior induced by the former may be strengthened by the enhanced mTOR effect of the latter, reinforcing neural circuits involved in executive control and decision-making, potentially counteracting the dysregulated reward pathways seen in addiction (Figure 3) [46,51]

The brand-name drug is prescribed to adults with obesity or overweight and should be used in combination with a reduced-calorie diet and increased physical activity

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The role of melatonin in immuno-enhancement: potential application in cancer