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Yes, in one larger human trial pasteurized Akkermansia increased GLP-1 in people with metabolic syndrome
Similarly, in controlled clinical studies in patients with type 2 diabetes mellitus, the antihyperglycemic effect of metformin was comparable in males and females

Some patients benefit from switching to oral semaglutide if injection-site reactions become too uncomfortable

Tirzepatide (Mounjaro and Zepbound) produces larger total weight loss than semaglutide on average, which means larger absolute muscle loss in numbers, even if the proportional loss is similar

Some potentially more severe side effects than Wegovy have been reported with Mounjaro, such as kidney and heart issues and an increased risk of some cancers

You might say, well, that's okay, because they're probably a big Pharmaceutical company that's very diversified with lots of different drugs
