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Yes, in one larger human trial pasteurized Akkermansia increased GLP-1 in people with metabolic syndrome

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Similarly, in controlled clinical studies in patients with type 2 diabetes mellitus, the antihyperglycemic effect of metformin was comparable in males and females

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Some patients benefit from switching to oral semaglutide if injection-site reactions become too uncomfortable

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Tirzepatide (Mounjaro and Zepbound) produces larger total weight loss than semaglutide on average, which means larger absolute muscle loss in numbers, even if the proportional loss is similar

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Some potentially more severe side effects than Wegovy have been reported with Mounjaro, such as kidney and heart issues and an increased risk of some cancers

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You might say, well, that's okay, because they're probably a big Pharmaceutical company that's very diversified with lots of different drugs

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