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Phase 1: During tapering Ensure adequate protein intake Adopt a sustainable low-carbohydrate or ketogenic diet and begin tracking ketones, along with glucose if you have diabetes or prediabetes Incorporate exercise, especially resistance training Phase 2: First 48 weeks after stopping Expect appetite to increase Maintain regular, structured meals using keto-friendly recipes Continue monitoring metabolic trends Phase 3: Long-term maintenance Use periodic tracking of your weight, ketones and/or glucose as needed Adjust food intake and activity based on your results How to Know If Youre Maintaining Fat Loss The Role of Muscle in Long-Term Success Preserving lean mass is an important component of long-term weight maintenance

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Clinical efficacy Efficacy and safety trials: SUSTAIN 17 The global program of clinical trial SUSTAIN (Semaglutide unabated Sustainability in Treatment of Type 2 Diabetes) included a series of Phase IIIA RCTs (SUSTAIN 15), designed to evaluate the efficacy and safety of semaglutide SC administered subcutaneously once a week in a range of people with T2DM, from those who have not received drugs to those who received oral antidiabetic drugs and/or insulin