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Conversely, the LIRAFLAME trial failed to show a significant effect of liraglutide compared to placebo on vascular inflammation as assessed by [18F]FDG PET after 26 weeks of treatment in people with T2DM [140]

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Some patients find that anxiety on GLP-1 reflects undiagnosed or undertreated underlying anxiety disorder, making concurrent psychiatric care essential

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( Epub 2014/12/06 )

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[16] [19] Subsequent analysis of SUSTAIN-6 data revealed that the increased risk was concentrated among patients who entered the trial with pre-existing diabetic retinopathy and experienced rapid improvements in glycemic control

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doi: 10.1056/NEJMoa1411892 26 ZangLLiuYGengJLuoYBianFLvXet al

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