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September 4, 2025 Arizona BOP inspection: A September 2025 inspection of Strives Gilbert, Arizona facility by the Arizona Board of Pharmacy found that Strive continued to compound and dispense single-ingredient versions of semaglutide and tirzepatide after the federal shortage exemption period ended

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Specifically, we found that the charges of the permeation enhancers and the peptides (which are directly controlled by the protonation states) are environment-dependent, which significantly affects the free energy change associated with membrane insertion of SNAC (Fig