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Hydration plays a crucial role in maintaining healthy bowel movements

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However, sustaining lifestyle changes is challenging, particularly in patients with multiple comorbidities [19] , prompting growing interest in pharmacologic interventions

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[10] [11] Additional safety considerations include caution in patients with severe gastroparesis, gallbladder disease, and a potential risk of diabetic retinopathy complications with rapid glucose improvement (particularly with semaglutide)