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1 Researchers acknowledged the genetic effect on weight loss was relatively small but said the findings lay the foundation for precision medicine approaches to obesity treatment by providing direct evidence that variation in drug-target genes contributes to differences in how patients respond

51 Gallbladder Disease Rapid weight loss can increase the risk of cholelithiasis and cholecystitis, and was observed in major GLP-1RA trials

Healthcare providers typically prescribe one medication at a time, and in some cases may switch from one to the other depending on a patients health goals and response to treatment

Common side effects of GLP-1 agonists include gastrointestinal symptoms such as nausea, diarrhea, and abdominal pain

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1D and Table 1)