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Serious adverse events and severe hypoglycaemia Neither tirzepatide nor semaglutide were associated with an increased risk for serious adverse events when compared with placebo (ESM Fig

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Hashimoto's thyroiditis Hashimoto's thyroiditis is one of the more commonly discussed autoimmune conditions in the context of GLP-1 medications, partly because thyroid function monitoring is already recommended for tirzepatide users due to the medication boxed warning about medullary thyroid carcinoma risk

A COA documents third-party testing of the medication for: Identity (confirming the medication is what the label says) Potency (confirming the concentration matches the label) Sterility (confirming no microbial contamination) Endotoxin levels (confirming safety for injection) pH and stability If your pharmacy cannot or will not provide a COA, consider whether you are comfortable using their products

It becomes an even greater threat if you have prior convictions on your record, particularly prior drug convictions