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Becoming pregnant while actively taking semaglutide is theoretically possible but not recommended due to limited human pregnancy safety data

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We believe that the receptor uses the ER as a bridge to access other cellular organelles, opening exciting possibilities to find new ways to improve diabetes therapies." Professor Alejandra Tomas Catala Department of Metabolism, Digestion and Reproduction The paper, published in Nature Communications, uncovers how the GLP-1 receptor (GLP-1R) forms a specialised signalling hub inside pancreatic -cells that supports healthy mitochondria and boosts insulin secretion

At the moment, this group is not covered by the NICE recommendations, which were made solely on the population included in the SELECT trial

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