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importantly, these actions of GLP-1 were attenuated as glucose concentrations approached 5 mmol/l [37]

Authors relationships and activities LJ reports receiving consulting and lecture fees from Abbott, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Medtronic, Merck, MSD, Novo Nordisk, Roche and Sanofi-Aventis

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The metabolic impact of tirzepatide throughout its weekly cycle is far more gradual and sustained than the sharp peaks and troughs that would be needed to meaningfully shift daily energy expenditure

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