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PEGylated GLP-1 exhibited a prolonged half-life and improved glycaemic control in diabetic mice

55 Together, the combined actions of various disorders in the proximal signaling components leads to impaired glucose metabolism and IR, and a major challenge remains for understanding IR mechanisms regarding how to distinguish the causes from insulin effects or primary defects from their consequences

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[1] Because no GLP-1 patches are currently FDA-approved or commercially available , there is no established clinical protocol for their application

Ben: Much less relevant

[DOI] [PubMed] [Google Scholar] 131.Tharakan G