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[DOI] [PMC free article] [PubMed] [Google Scholar] [10].Rasmussen L, Poulsen CW, Kampmann U, Smedegaard SB, Ovesen PG, Fuglsang J

Masetti M

[DOI] [PMC free article] [PubMed] [Google Scholar] 239.Shirani A, Stuve O
After PS matching, the mean diabetes duration in the GLP-1 RA group was 6.54.5 years, and the mean duration of GLP-1 RA treatment was 2.43.0 years

It's important to note that endogenous GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), giving it a very short half-life in circulation