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Wegovy, Zepbound, Saxenda, and other GLP-1 or GIP medications are needlessly out of reach for many Americans.

In an attempt to develop a strategy to prolong the physiological t1/2 and enhance the potency of GLP-1, a fusion protein consisting of active human GLP-1 and mouse IgG1 heavy chain constant regions (GLP-1/Fc) was generated

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