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Future research should prioritize long-term safety in underrepresented populations and strategies to mitigate lean mass loss during therapy

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These benefits are thought to arise from improved blood sugar and insulin regulation

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Some need a lower cash-pay option

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Per publicly available FDA and manufacturer announcements, the Wegovy pill (once-daily oral semaglutide 25mg) received FDA approval on December 22, 2025 and launched broadly across US pharmacies in January 2026 - the first oral GLP-1 receptor agonist approved for chronic weight management

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doi: 10.1016/j.lanepe.2024.100853

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Risk of aspiration pneumonitis after elective esophagogastroduodenoscopy in patients on glucagon-like peptide-1 receptor agonists

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