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Collectively, these data suggest that chronic treatment with a GLP-1R G-protein-biased agonist peptide maintains eWAT mass by increasing adipogenesis and prevents ectopic fat deposition in the liver induced by high-fat diet

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About 5% stopped at the lowest dose, 8% at the mid dose, and 10% at the highest dose, compared to about 3% with placebo

Secher A, Jelsing J, Baquero AF, Hecksher-Sorensen J, Cowley MA, Dalboge LS, Hansen G, Grove KL, Pyke C, Raun K, et al

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Government resistance to subsidising obesity medications and rising public scrutiny may slow broader uptake, despite clinical success and commercial demand