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After a 4-week run-in period in which participants were treated with diet and exercise alone, those who fulfilled the randomisation criteria were randomised (1:1:1:1) using a web-based randomisation system to receive once-daily oral semaglutide 3 mg, 7 mg or 14 mg or placebo for 26 weeks (using a 4-week dose-escalation regimen for the higher doses)

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Compounded semaglutide formulations often include B12 to support energy metabolism and reduce deficiency risk during weight loss therapy

Safetyfirst, individualized dosing.

Discover the evidence on interactions, gastrointestinal risks, and practical pain relief guidance for patients using semaglutide for weight management in the UK.