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Scheimann AO, Butler MG, Gourash L, Cuffari C, Klish W

Upper respiratory tract infections and nasopharyngitis are recognised adverse reactions in the UK SmPC that can present with sore throat symptoms

A combined effect that is bigger than just decreasing calories is thought to be at play when looking at the effects of activating the GLP-1 receptor.[ref] In overweight adults aged 45+, a 4-year-long study using semaglutide for weight loss also prevented HbA1c from rising over time, which was seen in the placebo arm

The overlapping side effect profiles and distinct mechanisms of action create risks that may be additive or synergistic