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A real-world analysis of approximately 8,000 patients from the Cleveland Clinic found considerably less weight regain than clinical trial data would predict largely because many real-world patients transition to another weight-loss agent, restart semaglutide, or maintain structured lifestyle interventions after stopping

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Makaronidis obtained funding from commercial organizations for the purpose of organizing conferences and educational events on behalf of the Association for the Study of Obesity (UK) in a voluntary role as the organizations sponsorship lead in 2025

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Many lawsuits against drug companies depend on showing a direct link between a medicine and harm