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Retatrutide has higher rates of nausea, diarrhea, and vomiting than tirzepatide
As a result, reactive oxygen species (ROS) production is induced, and nitric oxide (NO) levels are decreased (14)
Five clinical trials (SURPASS 1-5 trials) conducted in patients with T2DM showed that tirzepatide at 5-15 mg per week could reduce body weight (5.4-11.7kg), which was never seen with a single drug (129)
Salt and potassium are essential for the adrenal glands
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Wong M et al
