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Dulaglutide (100 nM) augmented the phosphorylation state of phospholamban at serine 16 and the phosphorylation state of the inhibitory subunit of troponin

Partly through these actions, GLP-1 receptor agonism was shown to reduce cardiovascular disease (CVD) in people with T2D with previous CVD or at high-risk thereof

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Key highlights from the 76-week study: Significant weight reduction: -13.0% mean weight loss in the 6.0-mg group vs -5.4% in placebo