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Appetite & energy-intake signaling: GLP-1 CS (Cagrilintide + Semaglutide) combines a GLP-1 receptor agonist with an amylin analog, commonly studied for complementary pathways related to satiety signaling, energy intake regulation, and glycemic-associated biomarkers

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doi: 10.1016/j.surg.2010.11.015 [DOI] [PMC free article] [PubMed] [Google Scholar] 21.Park AM, Storm DW, Fulmer BR, Still CD, Wood GC, Hartle JE, II

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Subsequently, PKA activity can augment the release of neurotransmitters into the synapse, facilitating long-term potentiation (LTP) and promoting cAMP-response element binding protein (CREB) phosphorylation, supporting cell growth/survival as well as synaptic plasticity [31, 33]