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Partly through these actions, GLP-1 receptor agonism was shown to reduce cardiovascular disease (CVD) in people with T2D with previous CVD or at high-risk thereof

Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent

Dont expect GLP-1 constipation to just go away on its own

At the same time, ultra-long-acting injectables are emerging as another theme of innovation

Januvia (sitagliptin) is an oral medication used to help manage type 2 diabetes

Berberine patches reviewed: what science says about effectiveness, how they compare to oral supplements, side effects, and safety guidance.
