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Among non-diabetic patients without chronic kidney disease (CKD), there was a minimal increase of 0.01 mg/dL to 0.02 mg/dL in serum creatinine in the months following initiation of semaglutide, liraglutide, or tirzepatide
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The first GLP-1 receptor agonist entered clinical use in 2005, marking a paradigm shift in metabolic disease treatment
