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Glucagon also contributes to energy homeostasis by promoting satiety through vagal signaling to brainstem nuclei and by increasing resting energy expenditure through facultative thermogenesis in brown adipose tissue, skeletal muscle, and through promotion of WAT browning [22]

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And beyond gastrointestinal effects, researchers are investigating concerns about long-term impact, such as gallbladder issues, pancreatitis and potential links to thyroid tumors

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These are all important factors to consider when talking to your healthcare provider about using these medications to lose weight