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Description
One noteworthy obstacle is the potential need for higher chemotherapy doses in obese patients based on their body weight

Additionally, a pooled analysis of large-scale clinical studies evaluating the cardiorenal advantages of GLP-1RAs in T2DM suggested a trend towards reduced pulmonary adverse events, including asthma, in the GLP-1RAs treatment groups [256]

Their success in managing both diabetes and obesity has been revolutionary, with GLP-1 RAs demonstrating substantially improved efficacy over last-generation interventions

However, FXR activation decreases both proglucagon mRNA levels and GLP-1 secretion in response to glucose [175, 176]

a Quality of evidence: Studies report their evidence to be of high certainty

They can help determine whether these medications are safe and appropriate for your specific situation
