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Most patients notice appetite changes within the first 12 weeks
Research indicates the impact on gastric emptying was greatest after a single dose of 5mg and diminished somewhat after subsequent doses as the body adapted

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Together, these two factors increase the risk of cholesterol buildup, which may turn into gallstones

This is the critical juncture

Mounjaro in addition to being a GLP-1 medication is also a glucose-dependent insulinotropic polypeptide (GIP) mimetic which Wegovy is not