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36 GLP-1R GLP-1R, a member of the GPCR family, exhibits specific affinity for GLP-1

What happens during this transition: Your metabolism slows down as you lose lean muscle mass Visceral fat (the deep abdominal fat around your organs) increases significantly Your risk of heart disease rises Glucose control can become more challenging, increasing diabetes risk Bone density starts to decline Weight gain during menopause is normal (but that doesnt make It easy) If youve been gaining weight during perimenopause or menopause, youre definitely not alone

It's usually felt in the upper right part of your abdomen, and it can spread to your back or right shoulder blade

Obesity can cause type 2 diabetes, heart disease, arthritis, fatty liver disease and certain types of cancer

The arrival of highly effective weight-loss medications has changed whats possible, but it has also changed our expectations

First-line management includes 30g daily dietary fibre, 1.52 litres of fluid, regular physical activity, and establishing a consistent toilet routine