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The licensing of oral semaglutide provided a step forward in type 2 diabetes management for this group, and the publication of the SOUL study in 2025 reassured us that oral semaglutide could also offer cardiovascular benefit in those at highest risk

The intensity of nausea typically correlates with dose escalation and tends to be most pronounced during the first few weeks of treatment or following dose increases

For some people, the gastrointestinal issues may persist even after theyve been on the medication for a while

Major US guidelines, including those from the American Gastroenterological Association (AGA) and the Endocrine Society, do not recommend or address this combination due to insufficient data

Auto-renews at 199/month after trial

But IBS is something that can be controlled