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In mice, obese mice showed greater neutrophilic airway inflammation with elevation of IL-6 levels in broncho-alveolar lavage (BAL) fluid, which was reduced by neutralizing antibodies for IL-6, indicating that IL-6 also has the potential to mediate obesity-induced asthma severity (84)

OCLC 1429657918

J Clin Invest 2021;131: e146353

In a subgroup analysis of 32 695 patients with preexisting DR, GLP-1 RAs were not associated with progression to proliferative DR (HR, 1.06

68 vs 72 weeks STEP-1 (NEJM 2021) vs SURMOUNT-1 (NEJM 2022) head-to-head body weight loss

Zepbound (tirzepatide) Zepbound is a newer medication indicated for chronic weight management