new oral glp 1 agonist Orforglipron, an Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes Oral GLP-1 receptor agonists: competition

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Robinson E, Cassidy RS, Tate M, Zhao Y, Lockhart S, Calderwood D, Church R, McGahon MK, Brazil DP, McDermott BJ

August 2019

J Diabetes Res (2020) 2020:8843310

Concurrently, Structure Therapeutics is advancing an APJ-targeting molecule into Phase 2 evaluation for obesity, suggesting that the target remains of clinical interest when candidate molecules are appropriately selected