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doi: 10.1016/j.ejphar.2020.173528 78 BornerTWorkingerJLTinsleyICFortinSMSteinLMChepurnyOGet al

The clinical picture is more complex than a simple hormone-equals-mood-fix relationship, but the association between perimenopausal hormonal changes and mood symptoms is well-documented

Researchers proceeding despite these unknowns must accept that they are operating without the safety data that clinical trials are designed to generate

And there are many reasons for this, including cost considerations, side-effect management, access considerations, and a general interest in GLP-1 therapies

Current and future treatments in alzheimer disease: an update