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If the solution remains cloudy after 15 minutes of intermittent gentle mixing, something may be wrong with the peptide, the water, or the process

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Historically described as mere fat-solubilizing agents, these amphipathic compounds were recently recognized as key signaling molecules capable to modulate the host metabolism directly acting as ligands of intestinal GPCRs (338, 339), or after being metabolized by the colonic microbiota into secondary bile acids, mostly deoxycholic and lithocholic acid(340)

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