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MHRA warnings have identified numerous products marketed for weight loss that contain unlicensed pharmaceutical ingredients, including banned substances like sibutramine or the industrial chemical DNP (2,4-dinitrophenol), which is illegal to sell for human consumption and can cause fatal overheating and organ failure

REFERENCES United States Food and Drug Administration

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Despite the widespread morbidity and mortality burden of HFpEF, current treatment options are limited, said corresponding author Nils Krger, MD, of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Womens Hospital, a founding member of the Mass General Brigham healthcare system

While the SAFE Drugs Act remains under legislative consideration, the FDA and state attorneys general appear to already be implementing more aggressive oversight measures until a more stringent oversight framework is in place