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GLP-1R agonists have a wide range of complex physiological effects due to the widespread expression of the GLP-1 receptors throughout the body 14

Sodium handling also shifts on semaglutide because the medication influences aldosterone signaling, a hormone that regulates salt balance

If your dosage needs to increase overtime, thats totally fine

Mol Nutr Food Res, 2016

Wegovy: Wegovy contains the GLP-1 receptor agonist semaglutide, the same active ingredient in Ozempic
