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Gestational DM Develops during pregnancy

Phentermine/topiramate is associated with the highest proportion of fatal cases (6% of its reported AEs)

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Headache GLP-1RAs are linked to reduced cerebrospinal fluid secretion and intracranial pressure due to their action on receptors in the choroid plexus, where they raise cyclic adenosine monophosphate (cAMP) levels and inhibit the Na+/K+ ATPase pump [91]

developed a balanced GLP-1 agonist/glucagon antagonist, ANC7K2 (structure not shown

The effect was initially thought to be secondary to reduced gastric emptying, however, it was later shown to be an independent effect (227, 228)