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Messier SP, et al
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Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial -Estrogen Receptor Expression and IGF-1/IGF-2 System
Instead, they looked at real world prescribing and outcomes, then tried to make the comparison groups as similar as possible
Finally, although genetic manipulation is one of the strengths of preclinical work, it is important to recognize that transgenic manipulations can induce developmental compensations in parallel pathways that can mask the overall effect of loss of the gene on surgical outcome
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