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35.Morais T., et al
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2016 GLP-1 , 13%, 22%
Therapeutic Advances in Drug Safety 9(3):171-178
The fraction of sitagliptin reversibly bound to plasma proteins is low (38%)

GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion