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GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda)along with tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, have transformed the management of type 2 diabetes and obesity

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As fat cells shrink under the influence of GLP-1 medications, they release stored contents into the surrounding tissue

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Only a head-to-head randomized controlled trial could definitively establish superiority, and that trial has not been conducted