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Oxyntomodulin is a 37-amino acid endogenous hormone secreted by intestinal L-cells postprandially

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Self-care for Mild Rectal Bleeding and Discomfort Increase dietary fibre intake and maintain good hydration Use stool softeners to reduce straining and avoid irritation of the anal area Take warm sitz baths Maintain good anal hygiene Medical Treatments for Persistent Rectal Bleeding or Pain Topical treatments to reduce inflammation and discomfort Pain relief medication, if appropriate Supplements such as iron, if the bleeding is leading to anaemia Surgical Options for Serious Rectal Bleeding Minimally invasive procedures such as rubber band ligation or sclerotherapy (injection) may be used to treat certain causes of rectal bleeding, particularly haemorrhoids

Retinopathy considerations : Rapid improvement in blood glucose control has been associated with temporary worsening of diabetic retinopathy

GLP-1 tablets for weight loss Medically reviewed by Dr Crystal Wyllie Last reviewed: 03 Jul 2026 The first GLP-1 tablet for weight loss is now available in the UK: the Wegovy pill, which contains semaglutide

Some patients may consider stopping after reaching target weight and establishing sustained lifestyle changes