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With more to offer than just blood sugar management, GLP-1s have become popular with health care providers and the public alike.

While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives

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Why the first non-peptide oral GLP-1 is drawing serious attentionand where caution still applies

The work of Lebrun et al now adds an important piece to this puzzle by describing a critical and previously unrecognized role for the gut-derived hormone glucagon-like-peptide 1 (GLP-1) in the regulation of intestinal inflammation

Discover How These Medications Help to Manage Obesity.