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PubMed Central, Femminella, Grazia Daniela, et al

According to Sinha et al., tirzepatide has better efficacy compared to many glucose-lowering medications such as dulaglutide, glargine, semaglutide, and insulin degludec and placebo drugs [14]

Now, both semaglutide and tirzepatide are FDA-approved both for diabetes and weight loss

P.PapadopoulosA
Similarly, 10 g/kg semaglutide treatment for 18 weeks reduced aortic plaque burden in mice with atherosclerosis induced by Pcsk9 overexpression (29)

The maximum dose is 14mg
