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Conclusions SGLT-2 inhibitors and GLP-1RA are superior to DPP-4 inhibitors in reducing the risk of most cardiorenal outcomes

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Conversely, a set of genesincluding Hsd11b1 , Camk2b , Aacs , and Atp1a3 were significantly downregulated, suggesting reduced activity or suppression of their associated biological functions

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Stress, illness, and sleep quality also influence glycaemic control independently of medication levels

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