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[1] The gastrointestinal effects of these medications, including delayed gastric emptying, can contribute to constipation

Lipids and fatty acids also stimulate incretin secretion via fatty acid receptors such as G-protein-coupled receptor (GPR) 40 and GPR119 [52, 53]

Much literature to date has focused on the risk for drug-induced acute pancreatitis attributed to hyperstimulation of acinar cells 14,15

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"For too long, we've judged, shamed, and blamed those living with obesity, treating their weight as their fault

Figure 3: Structure of the pancreas with Islet of Langerhans, credit: BruceBlaus, Wikimedia Knowledge about the pancreas deepened further as a result of research by Ernest Starling and his brother-in-law William Bayllis, two British physiologists at UCL