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Dysbiosis may develop due to a decline in beneficial taxa, while opportunistic species increase
-GLP-1 therapies dont act on fertility directly, but by improving metabolic and hormonal environments, they may support reproductive health
The soluble leptin receptor represents the main leptin-binding activity in human blood

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Recent concerns about pancreatitis and gallbladder disease warrant baseline assessment
In addition, subgroup analysis showed CKD and AKI reductions with SGLT2 inhibitors were most pronounced in individuals who did not have preexisting kidney disease
