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Higher ARB use in the GLP-1RA group may contribute modest positive confounding given evidence for ARB-mediated aortic protection

GLP-1 receptor agonists such as semaglutide are commonly prescribed for diabetes and obesity

( Eating disorders are on the rise in older womenand menopause is playing a role .) While the case reports are worrisome, McElroy says the GLP-1s themselves are not the issue

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Activation of LepRb NTS or GLP1 NTS neurons suppressed food intake and body weight.

Summary: Joint pain is not a common class-wide side effect of GLP-1 receptor agonists, though musculoskeletal symptoms are listed in some product summaries with varying frequency