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Studies show GLP-1 medications can reduce certain bacterial populations while expanding others, creating a temporary dysbiotic state in some patients

However, the classic symptoms of hyperthyroidism are not always present

After the initial 4 months, a subset of participants (270) continued the treatment for an additional 42 months in a single-blind extension phase, focused on weight maintenance

Based on estimates for drugs in development, the market size is from $20 3 to $40 4 billion

Hence, an accurate dose of levothyroxine is necessary to maintain the normal functioning of the thyroid for life